4 fab Lawrence moments from flubbed speech

By Randee Dawn, TODAY contributor

How is it possible for anyone to have as much self-possession and chutzpah as 22-year-old Jennifer Lawrence? Of course, it's a good thing she does -- the Oscar-winning actress does tend to fumble around a bit at awards ceremonies (who can forget her tumble at the Oscars) -- but thanks to her quick wit and inability to lose her cool she comes out on top.

The latest example to surface? Back in January, Lawrence accepted a best actress award for "Silver Linings Playbook" from the LA Film Critics, and the video of her speech had everyone cracking up -- but they were laughing with her, not at her. Here are four of the best moments from that less-than-four-minute speech:

Acknowledging her Bradley Cooper 'relationship'
"Silver Linings Playbook" co-star Cooper introduced Lawrence, then quickly scooted off the stage; her first comments were directed at him: "I just found out about our relationship in the tabloids today so I do think ... I think we should break up."

Sick of it
Lawrence was memorably ill during awards season; a flu she was battling at the Golden Globes blossomed into walking pneumonia by the SAG Awards. And during her speech, she's still coughing -- but joking about it. In the video, she's out of breath and coughing, apologizing to the crowd: "Sorry to everyone who I shook hands with, I'm sick so you're screwed."?

What a heel
Just after that apology, Lawrence is attempting to get back on track when she stumbles (despite not walking anywhere) and discovers the heel of her shoe has gone wonky: "God, sorry! I'm really not trying to like -- I'm sorry, I'm like all three of the Stooges right now. I'm on Sudafed, I'm sorry!"

Get back in the game
By the end of the speech, Lawrence is still holding on to her self-possession, but she's also starting to have trouble looking at the crowd. Fortunately, she's won them over and they're shouting back at her that she's "doing fine!" "Am I? I'm afraid to look at all of you. ... Shouldn't have looked at Bradley, that was a mistake," she says.

In the end, it's a primer on how not to get flustered during a speech. If Jennifer Lawrence can walk out in front of a roomful of critics, hopped up on cold medication and still remain this charming, anyone can. Go JLaw!?

Related content:

Source: http://todayentertainment.today.com/_news/2013/04/25/17911806-four-fabulous-jennifer-lawrence-moments-from-fumbled-speech?lite

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TokBox Brings WebRTC To The Cloud, Enables Multi-Party Video Chats & SIP Interop

Telefonica’s TokBox announced a huge upgrade to its OpenTok on WebRTC service today. TokBox’s new cloud-based Mantis media distribution framework is designed to overcome some of WebRTC’s limits with regard to video distribution. By default, WebRTC is a peer-to-peer platform, but that makes it hard to scale video chats beyond two participants. With Mantis, TokBox essentially puts its own cloud infrastructure in the middle of these calls and is then able to route and manage calls that include multiple participants without using a prohibitive amount of bandwidth and using a complicated mesh-based architecture. In the future, as TokBox CEO Ian Small told me earlier this week, this will also enable TokBox shape video streams according to the different users’ bandwidth conditions and the developers’ needs. “With Mantis, what we’re doing putting smarts into the WebRTC infrastructure,” Small said. “Today, we’re routing traffic. Tomorrow, we’ll shape traffic.” On cool feature Mantis already enables today is SIP interop, so developers will actually be able to write WebRTC-based apps that allow users to call in from their standard phone lines. This, for example, is useful for video conferencing services where you can now have a number of WebRTC-based video streams and a few participants on regular phone lines simultaneously. Currently, Small told me, the system scales well for chats with up to ten users. In a webinar setting where just one user is broadcasting, it can easily scale up to more than a hundred users. The company beta tested Mantis with the help of LiveNinja and Roll20. Current OpenTok developers won’t have to do anything to take advantage of the new system, given that TokBox already abstracts most of the WebRTC calls anyway. They will just have to create the topology they need for their apps (P2P, multi-party chat, etc.) and get started. It just “happens in the cloud automatically,” as Small noted, and now that it’s in the cloud, the company will be able to add many new features to its implementation in the near future. WebRTC, of course, is still in its early phases, something Small also acknowledged in our interview. In his view, we are not even in the early adopter phase right now. Instead, he believes, WebRTC is still in its experimentation and early mover phase. Once WebRTC arrives in the stable release channel of Firefox (it’s about to hit the developer channels soon and should be in the

Source: http://feedproxy.google.com/~r/Techcrunch/~3/wTQ9fSe290c/

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Samsung Galaxy S4 Review: The S Stands For Super, Not Simple

The Galaxy S4 has an easy mode, and more importantly, the Galaxy S4 needs an easy mode. This necessity is a double-edged sword. It means that the technology built into Samsung's latest generation smartphone does things you've never seen before, and maybe couldn't even imagine. However, really using that technology isn't as simple as you might think, and could be downright overwhelming to a novice smartphone user. This is the theme I kept running into with the GS4. If you're technologically advanced enough to be excited for hovering gestures and optical readers and two cameras working at the same time, then yes, you should absolutely jump on the Galaxy S bandwagon. But for those of you who want a phone that works well, keeps you connected, and not much else, be forewarned that the S in Galaxy S4 certainly doesn't stand for simple.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/LmqkECsIC3M/

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Demi Lovato and Taylor Swift Mashup: Listen Now!

Source: http://www.thehollywoodgossip.com/2013/04/demi-lovato-and-taylor-swift-mashup-listen-now/

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Mysterious Silly Putty Devours Innocent Magnets

If you're old enough to remember the movie The Blob, starring a gelatinous, oozing menace that gooped its way across floors, slid under doors, attached itself to an exposed foot, hand, arm and then devoured its screaming victim without making even a swallowing sound ... If you liked The Blob, then feast your eyes on this: Joey Shanks' Killer Silly Putty ... It's real ? and it eats magnets! (You don't have to watch the whole thing to get the idea ...)

Well, let's say it "swallows" magnets. What you have here is, in fact, Silly Putty, but doctored with a healthy sprinkling of mixed iron oxide powder. Iron, as you know, likes magnets. Iron and magnets attract. So when Joey Shanks who runs a production company in Chapel Hill was making this for Scott Lawson's YouTube Science and Engineering Channel he put a boron neodymium magnet next to the iron-rich Silly Putty. The magnet and the iron bits couldn't resist each other, and because Silly Putty is a fluid, it pretty much flows over the magnet and appears to "swallow it."

In real life, it does this rather slowly, taking a half hour, sometimes more, but Joey sped up the footage to create the illusion of a gelatinous monster devouring a hunk of metal (or in one poignant scene, an innocent happy-faced metal-boy).

What happens to the metal once it's inside the putty? Does it dissolve in a stew of putty digestive juices? No. Magnet lovers rest easy ? it's in there, whole, like Jonah inside the whale.

Does it sink to the bottom? Or stay near an edge, "hoping" to escape? Turns out, according to blogger Phil Plait, astronomer, lecturer, writing for Slate, ("It's Alive! ALIIIVVVEEE") the magnet keeps moving, deeper and deeper into belly of the puttyish mass until it reaches equilibrium, until there's roughly the same amount of iron top, bottom, left and right, holding it in place:

The process continued until the magnet was in the center, because it's only then that the forces are balanced. Newton's Second Law of Motion states that an unbalanced force on a mass will cause it to accelerate (though in this case that acceleration is itself balanced by the viscosity of the Silly Putty, leaving very slow but constant motion; it's like terminal velocity). As long as there's more iron on one side of the magnet than the other, it'll move. So eventually it reached the center of mass of the putty wad and stopped.

Which is wonderful, because now you can imagine yourself, being pretty much iron-free, grabbing onto the putty, ripping it open, reaching in, and heroically rescuing the magnet from its horrible fate ... like the hunter who rescues Little Red Riding Hood and her Grandma by slicing open the Big Bad Wolf! This is a physics lesson where you get to be a superhero. Is there anything better?

Well, dark chocolate is better. But that's another post.

Update: Hey! Commenty people, I'm sorry some of you (well, one of you ? "Captain Dave") don't like dark chocolate. No need to get persnickety, though, because in the end, you lose. Without dark chocolate, life is a pale thing. But since you are all wonderful, chocolate-loving or no, I thought I'd share this ? which just happened. When NPR producer Linda Holmes (who you may know from NPR's Monkey See blog) saw this post, she realized that by some crazy chance she happened to have her own iron-rich Silly Putty and a magnet.

Why? Linda told my producer, Andrew Prince, that she got them from a TV company, but not being sure what to do with them, she kept them in a can magnetically attached to a metal file cabinet next to her desk. But on seeing the video, she thought, "Ah, that's what they're for!" So she pulled the magnet out of its Silly Putty wrapper and brought them separately to Andrew and here, freshly minted, is Andrew's version of the same experiment. This may not be as exciting for you as it is for us, but how often do you get to see something cool in a video and get to repeat it, with all the parts handed you for free ? on the very same day? Life, sometimes, is just wonderful.

Andrew Prince/NPR/YouTube

The dodo belongs to Andrew. It's extinct, I know, but it still loves dark chocolate.

Source: http://www.npr.org/blogs/krulwich/2013/04/23/178615004/oh-the-horror-famished-silly-putty-devours-innocent-magnets?ft=1&f=1007

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New IU study: 'How' often is more important than 'why' when describing breakups

Public release date: 23-Apr-2013
[ | E-mail | Share ]

Contact: George Vlahakis
vlahakis@iu.edu
812-855-0846
Indiana University

BLOOMINGTON, Ind. -- Maybe rocker Greg Kihn was being prophetic in his 1981 hit, "The Breakup Song," with its chorus, "They don't write 'em like that anymore." An Indiana University professor's new paper looks at how people write to break up today, including through texts, emails and social media.

According to a new research article by Ilana Gershon, associate professor of communication and culture in IU's College of Arts and Sciences, part of what makes the breakup stories she collected into American stories is that the medium seems so important to the message when breaking off relationships.

"It wasn't until after I had collected many breakup stories that I realized my students had told me something quite revealing that would come up time and time again. ... American undergraduates focus on the 'how' of a breakup when describing their breakups, not the 'why' or the 'who,'" Gershon said.

Her paper, "Everytime We Type Goodbye: Heartbreak American Style," published in the journal Anthropology Now, discusses how the narratives of breakups in the United States differ from those in other countries.

Gershon also is the author of the 2010 book, "The Breakup 2.0: Disconnecting over New Media" (Cornell University Press), which argued that Facebook and other forms of social networking have radically changed the playing field of dating today.

She interviewed 72 people at length for her paper, including 66 undergraduate college students who communicate frequently with new technologies. She found that when American college students tell their breakup stories, they consist of a string of conversations, and people always describe when anyone switched media to continue the conversations.

"The medium used for the conversation mattered enough to be almost always mentioned," Gershon said. "People would invariably mark when a different medium was used, explaining when communication shifted from voicemail to texting to Facebook and then to phone."

Her results differ from other ethnographic research done elsewhere, such as in Japan and Britain, where the story often focuses on justifying why the relationship had to end. Character was the emphasis overseas, not the method.

"The American undergraduates I interviewed were not discussing their breakups in terms of the right balance of dependence, or even the kind of people who might break up," Gershon added.

"The closest an interviewee came to describing herself as a particular type of person was a woman who decided not to show anyone else the text breakup message her ex had sent her. Even this example shows that U.S. undergraduates were using the 'how' of the breakup as the narrative frame to explore what an end of the relationship might mean for them."

In many cases, the young people Gershon interviewed were looking for validation that it had been a bad breakup and the medium was crucial evidence.

In the paper, Gershon cited one example of a breakup done through a text message. "Rebecca" wanted to talk on the phone with her former boyfriend to have what she considered a "proper ending to the relationship."

"As in most of the narratives I collected, the 'how' of the breakup was the central focus of Rebecca's story," Gershon said. "This 'how' stood in for other questions that haunted Rebecca as well -- namely why her ex-boyfriend decided to break off the relationship.

"Rebecca and others did not focus on the 'why' of the breakup or the 'who' of the breakup, although this course would come up in the narratives as secondary themes," she said. "By focusing on the 'how,' she was able to avoid these often unanswerable questions -- unanswerable questions like why the breakup had happened in the first place and who really was to blame."

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 23-Apr-2013
[ | E-mail | Share ]

Contact: George Vlahakis
vlahakis@iu.edu
812-855-0846
Indiana University

BLOOMINGTON, Ind. -- Maybe rocker Greg Kihn was being prophetic in his 1981 hit, "The Breakup Song," with its chorus, "They don't write 'em like that anymore." An Indiana University professor's new paper looks at how people write to break up today, including through texts, emails and social media.

According to a new research article by Ilana Gershon, associate professor of communication and culture in IU's College of Arts and Sciences, part of what makes the breakup stories she collected into American stories is that the medium seems so important to the message when breaking off relationships.

"It wasn't until after I had collected many breakup stories that I realized my students had told me something quite revealing that would come up time and time again. ... American undergraduates focus on the 'how' of a breakup when describing their breakups, not the 'why' or the 'who,'" Gershon said.

Her paper, "Everytime We Type Goodbye: Heartbreak American Style," published in the journal Anthropology Now, discusses how the narratives of breakups in the United States differ from those in other countries.

Gershon also is the author of the 2010 book, "The Breakup 2.0: Disconnecting over New Media" (Cornell University Press), which argued that Facebook and other forms of social networking have radically changed the playing field of dating today.

She interviewed 72 people at length for her paper, including 66 undergraduate college students who communicate frequently with new technologies. She found that when American college students tell their breakup stories, they consist of a string of conversations, and people always describe when anyone switched media to continue the conversations.

"The medium used for the conversation mattered enough to be almost always mentioned," Gershon said. "People would invariably mark when a different medium was used, explaining when communication shifted from voicemail to texting to Facebook and then to phone."

Her results differ from other ethnographic research done elsewhere, such as in Japan and Britain, where the story often focuses on justifying why the relationship had to end. Character was the emphasis overseas, not the method.

"The American undergraduates I interviewed were not discussing their breakups in terms of the right balance of dependence, or even the kind of people who might break up," Gershon added.

"The closest an interviewee came to describing herself as a particular type of person was a woman who decided not to show anyone else the text breakup message her ex had sent her. Even this example shows that U.S. undergraduates were using the 'how' of the breakup as the narrative frame to explore what an end of the relationship might mean for them."

In many cases, the young people Gershon interviewed were looking for validation that it had been a bad breakup and the medium was crucial evidence.

In the paper, Gershon cited one example of a breakup done through a text message. "Rebecca" wanted to talk on the phone with her former boyfriend to have what she considered a "proper ending to the relationship."

"As in most of the narratives I collected, the 'how' of the breakup was the central focus of Rebecca's story," Gershon said. "This 'how' stood in for other questions that haunted Rebecca as well -- namely why her ex-boyfriend decided to break off the relationship.

"Rebecca and others did not focus on the 'why' of the breakup or the 'who' of the breakup, although this course would come up in the narratives as secondary themes," she said. "By focusing on the 'how,' she was able to avoid these often unanswerable questions -- unanswerable questions like why the breakup had happened in the first place and who really was to blame."

###

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-04/iu-nis042313.php

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Montana Democrat Baucus rules out 7th Senate term

Senate Finance Committee Chairman Sen. Max Baucus, D-Mont. leaves his committee office on Capitol Hill in Washington, Tuesday, April 23, 2013, saying that he was going to speak to the news media in his home state of Montana before discussing his retirement from the Senate. (AP Photo/J. Scott Applewhite)

Senate Finance Committee Chairman Sen. Max Baucus, D-Mont. leaves his committee office on Capitol Hill in Washington, Tuesday, April 23, 2013, saying that he was going to speak to the news media in his home state of Montana before discussing his retirement from the Senate. (AP Photo/J. Scott Applewhite)

Senate Finance Committee Chairman Sen. Max Baucus, D-Mont. leaves his committee office on Capitol Hill in Washington, Tuesday, April 23, 2013, saying that he was going to speak to the news media in his home state of Montana before discussing his retirement from the Senate. (AP Photo/J. Scott Applewhite)

FILE - In this Sept. 19, 2012 file photo, Senate Finance Committee Chairman Max Baucus, D-Mont. speaks reporters on Capitol Hill in Washington. According to Democratic officials: The six-term Democratic Sen. Max Baucus plans to retire. (AP Photo/J. Scott Applewhite, File)

FILE - In this April 17, 2013 file photo, Senate Finance Committee Chairman Sen. Max Baucus, D-Mont. speaks on Capitol Hill in Washington. According to Democratic officials: The six-term Democratic Sen. Max Baucus plans to retire. (AP Photo/J. Scott Applewhite, File)

Graphic profiles eight retiring U.S. senators

WASHINGTON (AP) ? Senate Finance Committee Chairman Max Baucus of Montana announced plans Tuesday to retire at the end of his term after a career of enormous power and notable independence, producing both collaboration and conflict with fellow Democrats on major tax and health care legislation.

"I don't want to die here with my boots on. There is life beyond Congress," the 71-year-old Baucus said in a telephone interview with The Associated Press.

He became the eighth senator to announce retirement plans for 2014, and the sixth Democrat. One public poll recently suggested he would have faced a difficult challenge if he had sought a seventh term.

Republicans must gain six seats in 2014 to win a majority, and they said the retirement enhanced their prospects.

Yet Democrats were cheered when former Democratic Gov. Brian Schweitzer, who recently stepped down after two terms, swiftly expressed interest in the race.

In a brief statement, President Barack Obama said Baucus "has been a leader on a broad range of issues that touch the lives of Americans across the country."

Sen. Chuck Grassley, an Iowa Republican and Baucus' frequent legislative partner, was complimentary, too. "We ran the Finance Committee for 10 years together, and every bill except for three or four was bipartisan," he said in a statement. "The Senate will be worse off as a deliberative body when Senator Baucus leaves."

In a written statement, Baucus sketched an ambitious agenda for the rest of his term, topped by an overhaul of the tax code.

"Our country and our state face enormous challenges - rising debt, a dysfunctional tax code, threats to our outdoor heritage and the need for more good-paying jobs," he said, adding several Montana-specific priorities as well.

Baucus, a fifth-generation Montanan, was elected to the Senate in 1978 after two terms in the House. He became the top Democrat on the Finance Committee in early 2001. He has held the position ever since on the panel ? which has jurisdiction over taxes, Medicare, Medicaid, health care and trade ? as chairman when his party held a majority and as senior member of the minority when Republicans were in power.

The panel has a long tradition of bipartisanship, but Baucus ascended to power in an era of increasing partisanship in Congress.

Many Democrats were unhappy when he worked with Republicans to enact the tax cuts that President George W. Bush won in 2001. And then again in 2004 when Congress pushed through a GOP plan to create a new prescription drug benefit under Medicare, a measure that most Democrats opposed as a giveaway to the large drug companies.

Baucus stood with fellow Democrats in 2005 when Bush proposed legislation to partially privatize Social Security, an epic battle that ended in defeat for the president's effort.

He played a central role in the enactment of Obama's watershed health care legislation in 2010, although some inside his party complained that precious momentum was lost while he spent months on bipartisan negotiations that ultimately proved fruitless.

More recently, Baucus has expressed opposition to Democratic proposals to use an overhaul of the tax code as a means of raising additional revenue. He was one of four members of his party to oppose the budget the leadership brought to the floor with a requirement to that effect.

On other issues large and small, Baucus' voting record reflected his rural state.

Most recently, he voted against legislation that Obama backed to expand background checks for gun purchasers.

During the debate on the budget, he was the only Democrat to vote for a proposal to reopen White House tours. Most members of his party viewed the GOP measure as an attempt to embarrass Obama, but it would also have meant more money for clearing snow from the entrances to Yellowstone National Park, a portion of which is in Montana.

For more than a decade, Baucus has sought federal assistance for the residents of Libby, Mont., where asbestos contamination from a vermiculite mine has been linked to deaths and illnesses.

Sen. Jon Tester, D-Mont., said he learned of the retirement plans on Monday. He said Baucus told him he wanted to return to Montana, and noted that if he waited until the end of his next term he would be nearly 80.

Baucus, in the interview with the AP, said: "Been here 40 years. No regrets. It is time to do something different."

Maneuvering began almost instantly for the 2014 race.

"The opportunity to try and get the country moving again like we did in Montana, that's appealing," said Schweitzer, who outpolled Baucus in a hypothetical matchup in the recent poll. "I'm a fixer."

Possible Republican candidates include former Gov. Marc Racicot; former Rep. Denny Rehberg, who lost to Baucus in 1996 and to Tester last fall; former Rep. Rick Hill and Rep. Steve Daines. State Sen. Champ Edmunds of Missoula and former state Sen. Corey Stapleton, had already announced they would run against Baucus.

"Montana is a state where Republicans can and will do well," said Sen. Jerry Moran of Kansas, the GOP campaign committee chairman, pledging to provide the resources needed to turn the seat Republican.

The state twice voted against Obama in presidential races. Despite the president's presence on the ticket in 2012, Tester won a second term in a hotly contested challenge, and another Democrat, Steve Bullock, was elected governor.

Sen. Michael Bennet, D-Colo., who heads the Democratic Senatorial Campaign Committee, touted last year's re-election of Tester and said, "We will continue to invest all the resources necessary to hold this seat."

Democrats will be defending 21 seats next year, compared with 14 for Republicans.

Baucus joined Jay Rockefeller of West Virginia, Frank Lautenberg of New Jersey, Tim Johnson of South Dakota, Tom Harkin of Iowa and Carl Levin of Michigan in announcing his retirement plans.

Republicans Saxby Chambliss of Georgia and Mike Johanns of Nebraska also have decided not to seek re-election next year.

___

Gouras reported from Helena. Associated Press writers Matthew Brown in Billings, Andrew Taylor, Donna Cassata and Alan Fram in Washington and Carson Walker in Phoenix contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-23-US-Baucus-Retirement/id-4c21e6984de34ef281040385b4dd4f97

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Everything You Need to Know About Apple?s Q2 earnings

Apple had an earnings call today, giving the low down on the company’s performance for its second quarter of 2013. The Cupertino company beat analyst estimates on a number of fronts, including total revenue and iPhone and iPad sales. We’re ...

Source: http://feedproxy.google.com/~r/GearFactor/~3/J7XrSMtuXGU/

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Stem cell transplant restores memory, learning in mice

Monday, April 22, 2013

For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember.

A study at the University of Wisconsin-Madison is the first to show that human stem cells can successfully implant themselves in the brain and then heal neurological deficits, says senior author Su-Chun Zhang, a professor of neuroscience and neurology.

Once inside the mouse brain, the implanted stem cells formed two common, vital types of neurons, which communicate with the chemicals GABA or acetylcholine. "These two neuron types are involved in many kinds of human behavior, emotions, learning, memory, addiction and many other psychiatric issues," says Zhang.

The human embryonic stem cells were cultured in the lab, using chemicals that are known to promote development into nerve cells ? a field that Zhang has helped pioneer for 15 years. The mice were a special strain that do not reject transplants from other species.

After the transplant, the mice scored significantly better on common tests of learning and memory in mice. For example, they were more adept in the water maze test, which challenged them to remember the location of a hidden platform in a pool.

The study began with deliberate damage to a part of the brain that is involved in learning and memory.

Three measures were critical to success, says Zhang: location, timing and purity. "Developing brain cells get their signals from the tissue that they reside in, and the location in the brain we chose directed these cells to form both GABA and cholinergic neurons."

The initial destruction was in an area called the medial septum, which connects to the hippocampus by GABA and cholinergic neurons. "This circuitry is fundamental to our ability to learn and remember," says Zhang.

The transplanted cells, however, were placed in the hippocampus ? a vital memory center ? at the other end of those memory circuits. After the transferred cells were implanted, in response to chemical directions from the brain, they started to specialize and connect to the appropriate cells in the hippocampus.

The process is akin to removing a section of telephone cable, Zhang says. If you can find the correct route, you could wire the replacement from either end.

For the study, published in the current issue of Nature Biotechnology, Zhang and first author Yan Liu, a postdoctoral associate at the Waisman Center on campus, chemically directed the human embryonic stem cells to begin differentiation into neural cells, and then injected those intermediate cells. Ushering the cells through partial specialization prevented the formation of unwanted cell types in the mice.

Ensuring that nearly all of the transplanted cells became neural cells was critical, Zhang says. "That means you are able to predict what the progeny will be, and for any future use in therapy, you reduce the chance of injecting stem cells that could form tumors. In many other transplant experiments, injecting early progenitor cells resulted in masses of cells ? tumors. This didn't happen in our case because the transplanted cells are pure and committed to a particular fate so that they do not generate anything else. We need to be sure we do not inject the seeds of cancer."

Brain repair through cell replacement is a Holy Grail of stem cell transplant, and the two cell types are both critical to brain function, Zhang says. "Cholinergic neurons are involved in Alzheimer's and Down syndrome, but GABA neurons are involved in many additional disorders, including schizophrenia, epilepsy, depression and addiction."

Though tantalizing, stem-cell therapy is unlikely to be the immediate benefit. Zhang notes that "for many psychiatric disorders, you don't know which part of the brain has gone wrong." The new study, he says, is more likely to see immediate application in creating models for drug screening and discovery.

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University of Wisconsin-Madison: http://www.wisc.edu

Thanks to University of Wisconsin-Madison for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127842/Stem_cell_transplant_restores_memory__learning_in_mice

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How Chrono24 Helps Bring Order To The Chaotic Watch Market

As TC's resident watch lover, I often find myself browsing the horology forums while alone, scantily-clad, and drunk. However, in this era of connoisseur-nets and always-conntected trade, there are few bargains to be found and even fewer ways to find exactly what you want. That's where Chrono24.com comes in. Founded by serial entrepreneurs Tim Stracke and Dirk Schwartz, the site has been live since 2003 but has just recently streamlined its operations to offer a sort of watch search engine that allows users to find timepieces of note from almost anywhere in the world.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Xv6u0q5HZ0M/

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Exclusive: Homeland Security deputy to quit; defended civilian Internet role (reuters)

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Google Play Store 4.0 redesign rolling out to Android phones and tablets today

Would news of an upcoming Google Play Store redesign completely blindside you? Of course not, but it's great to see it come to fruition sooner rather than later. The oft-whispered 4.0 update has now been officially acknowledged by Google and is ready for digital distribution starting today. What exactly is fresh and exciting about the new look? According to a blog post written by Play group product manager Michael Siliski, it focuses on bigger images, grouping together similarly themed content and offering new recommendations as you move down the page. Checkout has also been simplified just a tad. The update will be available for any phone or tablet running Android 2.2 or better, and it will begin rolling out today worldwide -- with such a hefty drain on Google's servers, however, the company warns that it may be a few weeks before it arrives on your particular device.

Filed under: Cellphones, Tablets, Wireless, Mobile, Google

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/NzgXgxnwzNQ/

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Maine gas prices down almost 6 cents per gallon

AUGUSTA, Maine (AP) -- Maine gas prices have plummeted nearly six cents per gallon in the past week, to an average of $3.64.

Price-monitoring website MaineGasPrices.com reports Monday the average retail gasoline price in Maine is now just six cents above the national average of $3.58.

In-state prices are now more than 33 cents lower per gallon than at the same time last year and nearly 15 cents per gallon lower than a month ago.

Nationally, prices are nine cents lower than a month ago.

The Maine price is based on a survey of more than 1,200 gas stations.

Source: http://news.yahoo.com/maine-gas-prices-down-almost-151713368.html

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Samoa airline introduces pay-by-weight pricing

PAGO PAGO, American Samoa (AP) ? A tiny Samoa airline is giving passengers a big reason to lose weight: tickets sold not by the seat, but by the kilogram.

Samoa Air planned on Wednesday to start pricing its first international flights based on the weight of its passengers and their bags. Depending on the flight, each kilogram (2.2 pounds) costs 93 cents to $1.06.

That means the average American man weighing 195 pounds with a 35-pound bag would pay $97 to go one-way between Apia, Samoa, and Pago Pago, American Samoa. Competitors typically charge $130 to $140 roundtrip for similar routes.

The weight-based pricing is not new to the airline, which launched in June. It has been using the pricing model since November, but in January the U.S. Department of Transportation approved its international route between American Samoa and Samoa.

The airline's chief executive, Chris Langton, said Tuesday that "planes are run by weight and not by seat, and travelers should be educated on this important issue. The plane can only carry a certain amount of weight and that weight needs to be paid. There is no other way."

Langton, a pilot himself, said when he flew for other airlines, he brought up the idea to his bosses to charge by weight, but they considered weight as too sensitive an issue to address.

"It's always been the fairest way, but the industry has been trying to pack square pegs into round holes for many years," he said.

Travelers in the region already are weighed before they fly because the planes used between the islands are small, said David Vaeafe, executive director of the American Samoa Visitors Bureau. Samoa Air's fleet includes two nine-passenger planes for commercial routes and a three-passenger plane for an air taxi service.

Langton said passengers who need more room will be given one row on the plane to ensure comfort.

The new pricing system would make Samoa Air the first to charge strictly by weight, a change that Vaeafe said is, "in many ways... a fair concept for passengers."

"For example, a 12- or 13-year-old passenger, who is small in size and weight, won't have to pay an adult fare, based on airline fares that anyone 12 years and older does pay the adult fare," he said.

Vaeafe said the pricing system has worked in Samoa but it's not clear whether it will be embraced by travelers in the U.S. territory.

Langton said the airline has received mixed responses since it began promoting the pricing on its website and Facebook.

Langton said some passengers have been surprised, but no one has refused to be weighed yet. He said he's given away a few free flights to some regular customers who lost weight, and that health officials in American Samoa were among the first to contact the airline when the pricing structure was announced.

"They want to ride on the awareness this is raising and use it as a medium to address obesity issues," he said.

Islands in the Pacific have the highest rates of obesity in the world. According to a 2011 report by the World Health Organization, 86 percent of Samoans are overweight, the fourth worst among all nations. Only Samoa's Pacific neighbors Nauru, the Cook Islands and Tonga rank worse.

In comparison, the same study found that 69 percent of Americans are overweight, 61 percent of Australians, and 22 percent of Japanese. Samoa ranked just as poorly in statistics measuring those who are obese, or severely overweight.

Samoa's Director General of Health, Palanitina Toelupe, said the airline's plans could be a good way to promote weight loss and healthy eating.

"It's a very brave idea on their part," she said.

She added that flying on the airline may become too expensive for some large people and that the charging system could only ever be a small part of a larger strategy on weight issues. She said she'd be interested in meeting with the airline to discuss working together.

Ana Faapouli, an American Samoa resident who frequently travels to Samoa, said the pricing scheme will likely be profitable for Samoa Air.

"Samoa Air is smart enough to find ways to benefit from this service as they will be competing against two other airlines," Faapouli said.

Pago Pago-based Inter Island Airways and Polynesian Airlines, which is owned by the Samoa government, also run flights between the country and American Samoa.

___

Perry reported from Wellington, New Zealand.

Source: http://news.yahoo.com/samoa-airline-introduces-pay-weight-pricing-231150753.html

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Green Pea galaxies could help astronomers understand early universe

Apr. 3, 2013 ? The rare Green Pea galaxies discovered by the general public in 2007 could help confirm astronomers' understanding of reionization, a pivotal stage in the evolution of the early universe, say University of Michigan researchers.

Reionization occurred a few hundred million years after the Big Bang as the first stars were turning on and forming the first galaxies. During this period, the space between the galaxies changed from an opaque, neutral fog to a transparent charged plasma, as it is today. Plasma is gas that's electrically charged.

As for how this happened, the prevailing theory holds that massive stars in the early galaxies produced an abundance of high-energy ultraviolet light that escaped into intergalactic space. There, the UV light interacted with the neutral hydrogen gas it met, blasting electrons off the hydrogen atoms and leaving behind a plasma of negatively charged electrons and positively charged hydrogen ions.

"We think this is what happened but when we looked at galaxies nearby, the high-energy radiation doesn't appear to make it out. There's been a push to find some galaxies that show signs of radiation escaping," said Anne Jaskot, a doctoral student in astronomy.

Jaskot and Sally Oey, an associate professor of astronomy in the College of Literature, Science, and the Arts, have found that the Green Peas could hold that evidence. Their findings are published in the current edition of the Astrophysical Journal.

"The Green Peas are compact, highly star-forming galaxies that are very similar to the early galaxies in the universe," Jaskot said. "Our analysis shows they may be leaking ionizing radiation."

The researchers focused on six of the most intensely star-forming Green Pea galaxies, which are between one billion and five billion light years away. They studied their emission lines as observed by the Sloan Digital Sky Survey. Emission lines show how light interacts with matter, and in this case, they helped the astronomers understand the relationship between the stars and gas in these galaxies.

The emission lines told Jaskot and Oey how much light the galaxies absorbed. Then, to determine how much light was there to start with, they ran models to estimate, for example, how old the galaxies are and how many stars they contain. The galaxies, the researchers determined, produced more radiation than the researchers detected, so they infer that some of it must have escaped.

"An analogy might be if you have a tablecloth and you spill something on it. If you see the cloth has been stained all the way to the edges, there's a good chance it also spilled onto the floor," Jaskot said. "We're looking at the gas like the tablecloth and seeing how much light it has absorbed. It has absorbed a lot of light. We're seeing that the galaxy is saturated with it and there's probably some extra that spilled off the edges."

Jaskot says the Green Peas are exciting candidates to help astronomers understand a major milestone in the development of the cosmos 13 billion years ago.

The paper is called "The Origin and Optical Depth of Ionizing Radiation in the 'Green Pea' Galaxies. The research is funded by the National Science Foundation.

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Journal Reference:

1. A. E. Jaskot, M. S. Oey. The Origin and Optical Depth of Ionizing Radiation in the "Green Pea" Galaxies. Astrophysical Journal, 2013 [link]

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/XdoUR4HhPC8/130403141446.htm

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Jane Levy Talks Evil Dead

Evil Dead





In the much anticipated remake of the 1981 cult-hit horror film, five twenty-something friends become holed up in a remote ca... Read More

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You might know Jane Levy as a nice suburban teen on "Suborgatory," but she's unrecognizable as the poster child for evil in "Evil Dead." She starts off as just a junkie looking to detox at the proverbial cabin in the woods, but then things literally go to hell when she's possessed by an ancient, bloodthirsty demon.

In the beyond-gory remake of the 1981 cult horror film, she takes over the lead role from Bruce Campbell, who gave the new cast his blessing.

Levy told Moviefone about the tough shoot, which included being buried alive, enduring a "blood rain," and spending more than a month in "evil" makeup. She admitted she wasn't much of a horror movie fan, but she is definitely game for more "Evil Dead."

Moviefone: It says in the press notes you're actually a "scaredy cat." So you're not a horror movie buff?
Levy: Not really, no. But I watched some after I got this job because I thought I should know about them.

Had you seen the original "Evil Dead?"
Mmm hmm. I watched it after I got the part and it made me more excited to be part of the project. I loved it.

The first one was actually fairly silly, but you go in a totally different direction with the remake.
It's a totally different direction, but there's the same fundamentals. The Book of the Dead and releasing the spirit and him taking the five souls.

How would you describe this version to fans of the original?
I would just tell them to give it a chance. I know they're going to see it. I know people's curiosity is going to get the better of them even if they don't want to, you know? It's its own movie. What's made me feel good about it is that the original creators are huge supporters of it. It's a "reimagining." People can see this movie without seeing the original. It's its own world.

Did you get any notes or advice from Sam Raimi or Bruce Campbell?
Bruce wrote the cast an e-mail when we started, saying, "This has been really tough and I'm passing the torch. Don't ever try to recreate anything we did, because" -- he was being humble -- "we weren't good actors back then." He was really sweet and his support has made me been able to get through the whole thing.

Do you think people were looking for a Bruce cameo?
I was expecting a Bruce Campbell cameo. I wanted it so bad.

I took a friend who's a huge horror movie fan to the screening and she said this was the most extreme horror movie she's ever seen. And I've been hearing about walkouts because it's just too intense for a lot of people. What's your reaction to that?
Yeah, we watched it at SXSW, it was the premiere. You can't ask for a better response from an audience. Nothing makes people so vocal. They were screaming and crying and laughing and cheering and whimpering. The energy in the theater was really fun. I started yelling myself.

Do you recognize yourself when you're made up as Evil Mia?
I guess so. I took so many pictures because the makeup was so intricate and beautiful, in some way. So I remember it all too well. I don't recognize my personality necessarily, but yeah, it's me up there. It's pretty fun to watch, actually. Kind of comical.

How do you keep things light on set when it's nothing but blood and mayhem all day long?
We didn't! Sometimes we did, but my biggest regret is I took it all so seriously. There's a way when the cameras are rolling to be that evil person and then be Jane right after, but I feel like I didn't have the skills to do that and from now on, in every movie I do -- you gotta keep it light when you're making something so heavy or else you're just going to get depressed.

What happened when you went home at night?
I didn't sleep. I had nightmares. We were so far away from home. It was the first time I'd been a lead in a movie and I'd worked so much. It all added up. But you've got to keep it light, when you're not filming, you've got to go get drunk or have one drink with a friend or watch a comedy. When we do number two, that's going to be my goal.

You're definitely coming back for the sequel?
Mmm hmm.

This already has elements of "Evil Dead 2" doesn't it?
I've never seen "Evil Dead 2." Sorry about that. I'm sorry to the world.

What was the most difficult day of filming for you?
Really hard to compare. Every day was some crazy thing. Being buried alive is something I'll be able to say for the rest of my life. I had blood squirted on my face and a plastic bag tied around my neck and an oxygen tube behind my ears so I wouldn't suffocate. And I got buried alive. I laid in the ditch until they covered me completely.

How long were you buried?
Once I was covered in dirt, I waited, like, two seconds and was able to dig myself out. It was just a layer of dirt over my face. I made sure I had my hands near my chest so I could immediately push the dirt off my face and rip the bag off my head.

So you had the toughest job on set?
Yeah, I think I had the toughest job. I worked the most out of anybody. Most people were in their evil makeup for a week, but I was in it for 37 days. I was just there forever.
And I also had to endure the blood rain at the end, which was in the middle of the night. Night shoots, winter, two weeks of it. I was alone, freezing cold, rolling around in the mud. It was hard.

Earlier on Moviefone:

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Source: http://www.rottentomatoes.com/m/1927165/news/1927165/

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NRA study suggests trained, armed school staffers

National School Shield Task Force Director, former Arkansas Rep. Asa Hutchinson gestures during a news conference at National Press Club in Washington, Tuesday, April 2, 2013, to discuss his groups's school-guns study. The National Rifle Association's study recommends schools across the nation each train and arm at least one staff member. (AP Photo/Jose Luis Magana)

National School Shield Task Force Director, former Arkansas Rep. Asa Hutchinson gestures during a news conference at National Press Club in Washington, Tuesday, April 2, 2013, to discuss his groups's school-guns study. The National Rifle Association's study recommends schools across the nation each train and arm at least one staff member. (AP Photo/Jose Luis Magana)

Mark Mattioli the father of a child killed during the Sandy Hook Elementary School shooting, gestures during a news conference at the National Press Club in Washington, Tuesday, April 2, 2013, where he talked about the National School Shield Task Force program. The National School Shield program is a frame work to arm security guards in any school system who want to be part of the program. (AP Photo/Jose Luis Magana)

National School Shield Task Force Director, former Arkansas Rep. Asa Hutchinson, holds a copy of group's study during a news conference at National Press Club in Washington, Tuesday, April 2, 2013. The National Rifle Association's study recommends schools across the nation each train and arm at least one staff member. (AP Photo/Jose Luis Magana)

WASHINGTON (AP) ? Schools across the nation should train selected staff members to carry weapons and should each have at least one armed security officer to make students safer and allow a quicker response to an attack, the director of a National Rifle Association-sponsored study said Tuesday.

Republican former Rep. Asa Hutchinson of Arkansas made the remarks as a task force he headed released its report, which included a 40- to 60-hour training program for school staff members who are qualified and can pass background checks.

"The presence of an armed security personnel in a school adds a layer of security and diminishes the response time that is beneficial to the overall security," said Hutchinson.

Asked if every school would be better off with an armed security officer, Hutchinson replied, "Yes," but acknowledged the decision would be made locally.

"Obviously we believe that they make a difference," he said.

Hutchinson said the security could be provided by trained staff members or by school resource officers ? police officers assigned to schools that some districts already have.

The report was released a week before the Senate plans to begin debating gun control legislation.

The NRA opposes the main feature of the legislation, an expansion of background checks to cover nearly all gun purchases. But the group has long said the school safety study would be an important response to last December's massacre of first-graders and staff members at an elementary school in Newtown, Conn.

At the White House, press secretary Jay Carney said administration officials were working with lawmakers to try to reach a compromise on legislation that could be supported by both parties.

"The president has always recognized that this is something that would be a challenge but that in the wake of the horrific shootings in Newtown was an obligation of all of us to work on and try to get done," Carney said.

The spokesman commented as the White House revealed the president plans a trip next week to Connecticut, scene of the horrific shooting that spurred the new push for gun-control legislation. The aim of Obama's trip is to build pressure on Congress to pass legislation.

Obama also plans to focus on firearms curbs in a trip Wednesday to Denver, not far from last summer's mass shooting in a movie theater in Aurora, Colo.

Obama and his allies ? mostly Democrats ? are trying to bolster prospects that Congress will approve gun legislation. Chances of such action on Capitol Hill have waned since the Newtown shootings.

The 225-page NRA study, which Hutchinson said cost more than $1 million, made eight recommendations. They included changing state laws that might bar a trained school staff member from carrying a firearm, NRA-provided online assessments that schools could make of their safety procedures and better coordination with law enforcement agencies.

The study drew immediate opposition from the American Federation of Teachers, which represents 1.5 million teachers and other workers.

"Today's NRA proposal is a cruel hoax that will fail to keep our children and schools safe," said AFT President Randi Weingarten. "It is simply designed to assist gun manufacturers" to flood the nation with more guns and large magazine clips.

Hutchinson said the NRA dropped an earlier recommendation that retired police officers and other volunteers be armed to provide school safety. He said the idea encountered "great reluctance" from school superintendents.

The NRA had suggested the retired officer idea just days after the Newtown killings.

Several NRA-supplied security guards were at Tuesday's event ? unusual for an announcement at the National Press Club, a building that houses offices for many news organizations.

Hutchinson said the NRA did not interfere with his task force's work. In a written statement, the NRA said the report "will go a long way to making America's schools safer."

Associated Press

Source: http://hosted2.ap.org/apdefault/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-02-US-Gun-Control/id-d477ffbf02b04a85875851eb4882109f

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Single-text e-reader review: a rising fad with long-term promise

Before Engadget was born, the late '90s saw a rising fear of the millennium bug, not to mention the advent of the first true e-readers. As time went on, e-ink technology on these devices improved, and despite the subsequent rise of tablets, e-readers have persisted thanks to their retina-soothing displays and generally affordable prices. Now, millions sit on bedside tables and in commuters' bags worldwide. Their popularity, however, has given rise to whole new branch of niche e-readers with tiny memories capable of holding but a single text. Join us as we delve into this fledgling fad and ask whether such low-cost hardware can persuade you to put down your Kindle, Nook or Kobo and give them a shot. Is this a new chapter in the e-reader story? Swing past the break and find out.

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Source: http://www.engadget.com/2013/04/01/dnp-single-text-e-reader-review-a-rising-fad-with-long-term-pro/

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Why Taking Action Doesn't Necessarily Produce Results?Freefall ...

Recently I posted a blog about my interpretation of the Law Of Attraction. In it I explained that manifesting without clarity, conviction and action delivers results that are at best questionable. What I didn?t fully explain is the futility if the vibration and?resonance of where you are operating is incongruent to that action.

I often receive a defensive response when I question people?s commitment. They automatically leap to justifying their positioning by explaining the amount of effort they have put into their endeavor. Lightbulb moment: Doing a lot or working hard does not necessarily guarantee results, in case you hadn?t noticed.

I was someone who spent many years DOING A LOT, working hard, putting in extreme effort, taking action up the ying yang. But I never realized I was creating a dysfunctional dynamic.? If anyone questioned my commitment, boy did I get offended ? ?you couldn?t meet anyone more committed than me,? I would think to myself. ?What was glaringly missing were the desired results, but at no point in all those years did I ever think it was because of me.? How could I be the one in the way when I was the one who was holier than thou with the level of action I was taking?it just did not compute.

So hear this from someone who knows:?Action (the ?doing? realm) augmented by vibration and resonance (the ?being? realm) is almighty powerful.?Can you achieve results if your vibration and resonance are not in alignment? YES. Do the results improve if you bring focus to where you are vibrating and resonating?TENFOLD! Yet I don?t see a lot being said about the relationship between action and energy?hence this post.

By vibration or resonance, I mean actions you take in alignment with your energetic beliefs. You need to claim the energy of what is yet to come, then play your part in bringing it to reality. That way you bring it to existence energetically well before it manifests in physical form. However, the energetic belief needs to be applied consistently. Think of it like driving your car. If positive vibrations are the accelerator, then incongruent vibrations are the brakes. Even after a sustained period of acceleration, you?ll bring your car to an abrupt stop if you apply the brakes. At the same time, once your car is bowling along at a good speed, it takes very little acceleration to keep the momentum going.

So what do I recommend?

Tune in to what you believe. And let go of notions of resistance and trial. I always used to think that the universe was testing me. But many years ago I realized that this is not possible.?I now believe the universe NEVER tests us. We however test the universe CONSTANTLY?we question our faith when things do not seem to be going the way we anticipated. Here?s a concept: consider that?whatever you perceive as ?not working right now? is exactly as it needs to be.

That may lead you to tuning in to something bigger. For example, humans ?are 60-70% water. It seems obvious to me that we are impacted by tidal cycles?which are in turn impacted by lunar cycles.? We are part of the whole; there is no separateness.

I wrote today?s blog to give you leverage for getting more effective results by grounding some ethereal new age concepts.

I trust it will help you align your energy with your actions, and generate the results you seek in your life.

If you are ready for more effective results in your life, contact us?or book in for a free 1 hour, no obligation consultation with a?Certified Freefall Coach?

Source: http://www.freefallselfimprovement.com/why-taking-action-doesnt-necessarily-produce-results/

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Wanderlei Silva pulls April Fool?s ?joke,? says he?s fighting Gegard Mousasi at UFC on Fuel. He?s not.

As we mentioned on Monday, Saturday's main event UFC bout between Gegard Mousasi and Alexander Gustafsson could be in trouble because of a facial laceration suffered by Gustafsson. Wanderlei Silva saw this news, and seized upon it to play an April Fool's Joke that wasn't really all that funny.

He tweeted this info late Monday afternoon:

UFC news my guys fight Saturday agains Musasi!!! What you think? UFC just contact me about Saturday,UFC acabeu de me ligar o que acha?

? Wanderlei Silva (@wandfc) April 1, 2013

No one from the UFC confirmed that Silva was taking Gustafsson's place, but Silva kept playing up the "joke." He tweeted news stories about him taking the fight. Even Mousasi tweeted about it:

@ufc @danawhite at this moment I do not have any new info about my situationBut if ufc want's and mr @wandfc is ready for me than let's Go!

? Gegard Mousasi (@mousasi_mma) April 1, 2013

But on Tuesday morning, Silva admitted it was a joke. He posted the above picture on his Instagram account, with the caption:

I catch you wand the best April first ever!! But I would like this to be true!!!

Ummm, OK. For one, is that funny? The MMA website Middle Easy pulled a good April Fool's Day prank by redesigning their website as if it was 1996. Hulu changed all their show titles to fake shows like "The Rural Juror" and "Ya Herd? With Perd." But saying you have a fight when you don't?

If Silva wants to say he is next man up for the bout with Mousasi in case Gustafsson can't fight, that's fine. He should just do that. But taking everyone in the MMA world, even a potential opponent, for a ride with a so-called joke? That's not cool, Axe Murderer.

Source: http://sports.yahoo.com/blogs/mma-cagewriter/wanderlei-silva-pulls-april-fool-joke-says-fighting-145339633--mma.html

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